产品说明
一般描述
Mouse BID cleaved with caspase-8 generates the amino-terminal fragment (amino acids 1-59, 7 kDa) and the carboxy-terminal fragment (amino acids 60-195, 15 kDa). On size exclusion chromatography cleaved BID elutes at 27 kDa indicating that the fragments remain associated.
生化/生理作用
Caspase-8-cleaved BID relocates from the cytosol to the outer mitochondrial membrane where its interaction with Bak alters mitochondrial membrane permeability.
外形
0.2 μm filtered solution in 25 mM HEPES, pH 7.5, and 0.1 M KCl.
分析说明
Measured by its ability to induce cytochrome c release from isolated mouse liver mitochondria.
基本信息
| MDL编号 | MFCD03456214 |
| NACRES | NA.32 |
产品性质
| 质量水平 | 200 |
| 重组 | expressed in E. coli |
| 测定 | ≥95% (SDS-PAGE) |
| 形式 | buffered aqueous solution |
| UniProt登记号 | P70444 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | mouse ... Bid(12122) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
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