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Monoclonal Anti-Calcitonin Gene-Related Peptide antibody produced in mouse

抗-降钙素基因相关肽单克隆抗体 小鼠抗

品牌
Sigma-Aldrich
货号
C9487
规格纯度
clone CD8, purified immunoglobulin, buffered aqueous solution
参考价格
6766.41 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Monoclonal Anti-Calcitonin Gene-Related Peptide antibody produced in mouse
Anti-CGRP
抗-降钙素基因相关肽单克隆抗体 小鼠抗
抗 CGRP
产品介绍:

产品说明

一般描述

Calcitonin gene-related peptide (CGRP) is a vasodilator that belongs to the calcitonin family of peptides. It is produced by motor neurons of peripheral and central nervous system. There are two forms of CGRP, α and β, which exhibit similar functions. The effects of CGRP are mediated by G-protein coupled receptor heterodimer formed by calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein 1 (RAMP1). Several biological effects of CGRP are observed in nervous, endocrine, immune and cardiovascular systems. Multiple studies have implicated CGRP in the pathophysiology of migraine and antagonists to CGRP are being explored as treatment options
Monoclonal Anti-Calcitonin Gene-Related Peptide (CGRP) recognizes human and guinea pig CGRP. It does not cross react with rat CGRP.

免疫原

peptide corresponding to the C-terminal of rat α−calcitonin gene-related peptite (CGRP).

应用

Anti-Calcitonin Gene-Related Peptide (CGRP) antibody is suitable for immunohistochemistry at a working antibody dilution of 1:200 to 1:1000 using formalin-fixed, paraffin-embedded sections or cryostat tissue sections. The antibody may be used for immunofluorescence at a working dilution of 1:500.

外形

Solution in PBS containing 1% BSA and ≤ 0.1% sodium azide

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD00162203
NACRESNA.41

产品性质

质量水平200
生物来源mouse
偶联物unconjugated
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆CD8, monoclonal
形式buffered aqueous solution
species reactivityguinea pig, human
technique(s)immunocytochemistry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:200-1:1,000 using ovenight incubation at 4 ℃ and sections that have been protease-digested or processed by high temperature antigen retrieval
indirect immunofluorescence: 1:500 using overnight incubation at 4 ℃
同位素/亚型IgG1
UniProt登记号P01258
运输dry ice
储存温度−20℃
Gene Informationhuman ... CALCA(796)
rat ... Calca(24241)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Sigma-Aldrich

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