产品说明
一般描述
Phosphocholine is considered as a precursor molecule. It is formed during the breakdown of phosphatidylcholine metabolism.
Avanti′s nitroxide spin product listing is a group of compounds designed to act as membrane probes. A variety of positions down the hydrophobic chain are labeled with the nitroxide functional groups to allow probing the membrane at various depths. These compounds have been synthesized from 1-palmitoyl-2-hydroxy-sn-glycerol-3-phosphocholine with the product being purified by column chromatography. Various n-doxyl phosphocholines have been recently used as biophysical tools to elucidate membrane trafficking with phosphatidylinositol transfer proteins and as fluorescent quenchers in lipid bilayer structural studies.
应用
16:0-10 Doxyl PC may be used in vesicles for quenching PT-(1–46)F4W fluorescence. It may also be used in vesicles to check the fluorescence emission spectra in order to measure the penetration depth of the peptides′ tryptophan residues in lipid bilayer.
生化/生理作用
Phosphatidylcholine (PC) lowers the levels of cholesterol and triglycerides.
包装
5 mL Clear Glass Sealed Ampule (810603C-1mg)
制备说明
Product use: To prevent aggregation, prepare water-based solutions of 2 mM stock solutions of n-DOXYL PCs and store in plastic. Dilute stock solutions to 0.03- 0.1 mM solutions for EPR studies. For liposome preparations in fluorescent quenching measurements, dissolve the doxyl lipid in 150 μl absolute ethanol for a concentration of 40.3 mM , Additional supplemental information.
基本信息
| 经验(实验)分子式 | C46H90N2O10P |
| 分子量 | 862.19 |
产品性质
| 测定 | >99% (TLC) |
| 包装 | pkg of 1 × 1 mL (810603C-1mg) |
| manufacturer/tradename | Avanti Polar Lipids 810603C |
| 浓度 | 1 mg/mL (810603C-1mg) |
| 运输 | dry ice |
| 储存温度 | −20℃ |
安全信息
| 象形图 |   |
| 警示用语： | Danger |
| 危险声明 | H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 - H412 |
| 预防措施声明 | P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313 |
| 危险分类 | Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3 |
| 靶器官 | Central nervous system |
| 储存分类代码 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
| WGK | WGK 3 |
| 闪点(F) | does not flash |
| 闪点(C) | does not flash |
Sigma-Aldrich
m.cnreagent.com
