产品说明
一般描述
Casein Kinase 2 (CK2) is a ubiquitously expressed serine/threonine kinase that has been implicated in various cellular functions such as cell death, cell cycle regulation, and mRNA synthesis. This protein kinase comprises of two catalytic α subunits and two dimeric β subunits that associate to form a heterotetrameric enzyme complex.CK2 is also involved in regulating viral infections
Monoclonal Anti-Casein Kinase 2β antibody is specific for human, bovine, rat, mouse and hamster Casein Kinase 2β (approx. 30 kDa). The antibody epitope lies within amino-acids 123-127 of human CK2β.
免疫原
recombinant human casein kinase 2β (CK2β). The antibody epitope resides within amino acids 123-127.
应用
Monoclonal Anti-Casein Kinase 2β antibody is suitable for use in indirect immunofluorescence (using A549 cells ). The product can also be used for western blot (2-4 μg/mL using total cell extract of HepG2 cells), microarray, dot blot and indirect ELISA.
生化/生理作用
Casein Kinase 2β encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha pr
外形
0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
MDL编号 | MFCD00675215 |
NACRES | NA.44 |
产品性质
质量水平 | 200 |
生物来源 | mouse |
偶联物 | unconjugated |
抗体形式 | purified immunoglobulin |
antibody product type | primary antibodies |
克隆 | 6D5, monoclonal |
形式 | buffered aqueous solution |
分子量 | antigen ~30 kDa |
species reactivity | human, bovine, rat, hamster, mouse |
浓度 | ~2 mg/mL |
technique(s) | dot blot: suitable indirect ELISA: suitable microarray: suitable western blot: 2-4 μg/mL using total cell extract of HepG2 cells |
同位素/亚型 | IgG1 |
UniProt登记号 | P67870 |
运输 | dry ice |
储存温度 | −20℃ |
Gene Information | human ... CSNK2B(1460) mouse ... Csnk2b(13001) rat ... Csnk2b(81650) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |