产品说明
一般描述
C6-NBD Glucosyl Ceramide is a fluorescent derivative of biologically active compound, glucosyl ceramide. Glucosyl ceramide belongs to the class of sphingolipids that are synthesized in the cis/medial-Golgi apparatus by the glycosylation of ceramide.
应用
C6-NBD Glucosyl Ceramide may be used as a substrate for glucocerebrosidase (GCase) activity assay in Drosophila melanogaster and mice.
生化/生理作用
Glucosylceramide is the precursor of different glycosphingolipids including gangliosides and sulfatides. Glucosyl ceramide is also known to be responsible for axon growth of neural cells. The accumulation of glucosyl ceramide is associated with an inherited lysosomal storage disorder, Gaucher′s disease.
包装
5 mL Clear Glass Sealed Ampule (810222C-250ug)
基本信息
| 经验(实验)分子式 | C36H59N5O11 |
| 分子量 | 737.88 |
| NACRES | NA.25 |
产品性质
| 测定 | >99% (TLC) |
| 包装 | pkg of 1 × 1 mL (810222C-250ug) |
| manufacturer/tradename | Avanti Polar Lipids 810222C |
| 浓度 | 0.25 mg/mL (810222C-250ug) |
| 运输 | dry ice |
| 储存温度 | −20℃ |
安全信息
| 象形图 |   |
| 警示用语： | Danger |
| 危险声明 | H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 |
| 预防措施声明 | P201 - P260 - P264 - P280 - P304 + P340 + P311 - P403 + P233 |
| 危险分类 | Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3 |
| 靶器官 | Central nervous system |
| 储存分类代码 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
| WGK | WGK 3 |
| 闪点(F) | does not flash |
| 闪点(C) | does not flash |
Sigma-Aldrich
m.cnreagent.com
