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Anti-TCR beta chain (mouse), FITC, clone H57-597 Antibody

品牌
Sigma-Aldrich
货号
MABF145C
规格纯度
clone H57-597, from hamster(Armenian), FITC conjugate
参考价格
1415.25 *本价格含增值税费
促销
服务
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  • 增值税票
数量
-+
产品名称:
Anti-TCR beta chain (mouse), FITC, clone H57-597 Antibody
Pre T-cell antigen receptor alpha, TCR beta chain
产品介绍:

产品说明

一般描述

The H57-597 antibody is specific for the beta chain of the mouse T cell Receptor (TCR). This cell surface protein combines with a second protein chain (alpha chain) to form the alpha-beta TCR that is expressed by NK1.1+ thymocytes, NKT cells, and the majority of peripheral T cells. A small number of T cells may express an alternative heteromer of gamma/delta protein chains, known as the g/d TCR. These receptors participate in a complex with CD3, and with the co-receptors CD4 or CD8, to recognize and respond to antigens bound to MHC molecules on antigen-presenting cells. Such interactions promote T cell receptor signaling (T cell activation) and can result in a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death.The H57-597 antibody is used as a phenotypic marker for T cells expressing the alpha-beta TCR. It is also widely used to cross-link surface TCR and thereby mimic TCR-mediated cell activation or induction of apoptosis. The antibody does not cross-react with cells expressing the g/d TCR.

免疫原

Immunogen information for this antibody is proprietary information.

应用

Research Sub Category
Immunoglobulins & Immunology
This armenian hamster monoclonal Anti-TCR beta chain Antibody (mouse), FITC, clone H57-597, Cat. No. MABF1454 is validated for use in Flow Cytometry, for the detection of TCR beta chain.
Research Category
Inflammation & Immunology

质量

This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

Flow Cytometry Analysis: 0.25 μg from a representative lot detected TCR beta chain in one million C57Bl/6 splenocytes.

外形

Purified Armenian Hamster monoclonal containing 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2.
Purified by size-exclusion chromatography

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.
Note: It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.

其他说明

Concentration: Please refer to lot specific datasheet.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702

产品性质

生物来源hamster (Armenian)
质量水平100
偶联物FITC conjugate
抗体形式purified antibody
antibody product typeprimary antibodies
克隆H57-597, monoclonal
species reactivitymouse
包装antibody small pack of 25 μg
technique(s)flow cytometry: suitable
同位素/亚型IgG
UniProt登记号P0C6B2

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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