产品说明
应用
1,1-Dimethyl-4-phenylpiperazinium iodide (DMPP) has been used as a non-selective nicotinic acetylcholine receptor (nAchR) agonist:
包装
1, 10 g in glass bottle
生化/生理作用
1,1-Dimethyl-4-phenylpiperazinium iodide (DMPP) is a non-selective nicotinic acetylcholine receptor (nAchR) agonist. It acts as a stimulating agent for sympathetic ganglia. DMPP exhibits specific action on ganglia and adrenal medullary tissue hence, it finds its application in the diagnosis of pheochromocytoma.
特点和优势
This compound is featured on the Acetylcholine Receptors (Nicotinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
基本信息
经验(实验)分子式 | C12H19IN2 |
分子量 | 318.20 |
Beilstein | 3746109 |
EC 号 | 200-213-0 |
MDL编号 | MFCD00011976 |
PubChem化学物质编号 | 24277832 |
NACRES | NA.77 |
产品性质
质量水平 | 200 |
测定 | ≥98% (TLC or titration) |
mp | 234-238 ℃ (lit.) |
溶解性 | H2O: 21 mg/mL |
储存温度 | −20℃ |
SMILES string | [I-].C[N+]1(C)CCN(CC1)c2ccccc2 |
InChI | 1S/C12H19N2.HI/c1-14(2)10-8-13(9-11-14)12-6-4-3-5-7-12;/h3-7H,8-11H2,1-2H3;1H/q+1;/p-1 |
InChI key | XFZJGFIKQCCLGK-UHFFFAOYSA-M |
Gene Information | human ... CHRNA1(1134), CHRNA10(57053), CHRNA2(1135), CHRNA3(1136), CHRNA4(1137), CHRNA5(1138), CHRNA6(8973), CHRNA7(1139), CHRNA9(55584), CHRNB1(1140), CHRNB2(1141), CHRNB3(1142), CHRNB4(1143) rat ... Chrna2(170945), Chrna3(25101), Chrna4(25590), Chrnb2(54239), Chrnb4(25103) |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
Sigma-Aldrich