产品说明
一般描述
Dilazep comprises central cyclic diamine and phenyl rings connected via alkyl linkers.
应用
Dilazep dihydrochloride has been used in estrogen receptor (ERα) antagonistic assay. It has also been used as an equilibrative nucleoside transporter inhibitor (ENT 1 and 2) in cancer cell lines.
包装
100 mg in glass bottle
50 mg in poly bottle
生化/生理作用
Dilazep is a equilibrative nucleoside transporter 1 (ENTs) inhibitor. It is an antianginal drug and an effective coronary vasodilator. Dilazep elicits anti-albuminuric effects and is an anti-platelet agent. It is a potent adenosine uptake inhibitor and suppresses effects of ischemia.
基本信息
| 经验(实验)分子式 | C31H44N2O10 · 2HCl |
| 分子量 | 677.61 |
| EC 号 | 243-548-8 |
| MDL编号 | MFCD00133267 |
| PubChem化学物质编号 | 24278372 |
| NACRES | NA.77 |
产品性质
| 形式 | powder |
| 质量水平 | 200 |
| 颜色 | white |
| 溶解性 | H2O: 10 mg/mL |
| 储存温度 | 2-8℃ |
| SMILES string | Cl[H].Cl[H].COc1cc(cc(OC)c1OC)C(=O)OCCCN2CCCN(CCCOC(=O)c3cc(OC)c(OC)c(OC)c3)CC2 |
| InChI | 1S/C31H44N2O10.2ClH/c1-36-24-18-22(19-25(37-2)28(24)40-5)30(34)42-16-8-12-32-10-7-11-33(15-14-32)13-9-17-43-31(35)23-20-26(38-3)29(41-6)27(21-23)39-4;;/h18-21H,7-17H2,1-6H3;2*1H |
| InChI key | VILIWRRWAWKXRW-UHFFFAOYSA-N |
| Gene Information | human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140) |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H315 - H319 - H335 |
| 预防措施声明 | P302 + P352 - P305 + P351 + P338 |
| 危险分类 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| 靶器官 | Respiratory system |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
Sigma-Aldrich
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