产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
DPPE is a potent, selective ligand of the microsomal anti-estrogen binding site. DPPE is a tamoxifen derivataive that binds with high affinity to the anti-estrogen binding site, but unlike tamoxifen, does not bind to the estrogen receptor. DPPE sensitizes MDR tumor cells to chemotherapy and also inhibits histamine binding at the intracellular histamine site.
特点和优势
This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
基本信息
经验(实验)分子式 | C19H25NO·HCl |
分子量 | 319.87 |
MDL编号 | MFCD11114012 |
PubChem化学物质编号 | 329798745 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | powder |
颜色 | white |
溶解性 | H2O: 16 mg/mL |
储存温度 | 2-8℃ |
SMILES string | Cl.CCN(CC)CCOc1ccc(Cc2ccccc2)cc1 |
InChI | 1S/C19H25NO.ClH/c1-3-20(4-2)14-15-21-19-12-10-18(11-13-19)16-17-8-6-5-7-9-17;/h5-13H,3-4,14-16H2,1-2H3;1H |
InChI key | TXLHNFOLHRXMAU-UHFFFAOYSA-N |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | nwg |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich