DS1

产品名称：

372497-52-4
DS1
4-Chloro-N-[6,8-dibromo-2-(2-thienyl)imidazo[1,2-a]pyridine-3-yl]benzamide

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

δ-GABA_A receptors are emerging as an important pharmacological target. DS1 potently (low nM) enhances GABA-evoked currents mediated by α4β3δ receptors. It had little effect on GABA responses mediated by α4β3γ2 receptors. At similar concentrations DS1 directly activates this receptor and is the most potent known agonist of α4β3δ receptors. This compound has an opportunity to be become an agonist golden stardard for δ-GABA_A receptors.
DS1 potently (low nM) enhances GABA-evoked currents mediated by GABA_A α4β3δ receptor subtype. At similar concentrations, it acts as a direct agonist at this receptor and is the most potent agonist known. It has little effect on GABA responses mediated by α4β3γ2 receptors.

基本信息

经验(实验)分子式	C₁₈H₁₀Br₂ClN₃OS
分子量	511.62
MDL编号	MFCD01943217
PubChem化学物质编号	329798608

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
储存条件	desiccated
颜色	off-white to tan
溶解性	DMSO: >10 mg/mL
储存温度	2-8℃
SMILES string	Clc1ccc(cc1)C(=O)Nc2c(nc3c(Br)cc(Br)cn23)-c4cccs4
InChI	1S/C18H10Br2ClN3OS/c19-11-8-13(20)16-22-15(14-2-1-7-26-14)17(24(16)9-11)23-18(25)10-3-5-12(21)6-4-10/h1-9H,(H,23,25)
InChI key	MEWSBNIVOLYKGU-UHFFFAOYSA-N