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Anti-Endothelin Receptor A antibody produced in rabbit

抗-内皮素受体A 兔抗

品牌
Sigma-Aldrich
货号
E3651
规格纯度
affinity isolated antibody, lyophilized powder
参考价格
3774.88 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-Endothelin Receptor A antibody produced in rabbit
Anti-ET1-Specific Endothelin Receptor
Anti-ET-A
抗-内皮素受体A 兔抗
产品介绍:

产品说明

特异性

The epitope is highly conserved in human, swine, bovine and chicken ET-A.

免疫原

synthetic peptide corresponding to amino acids 413-426 of rat ET-A (with additional N-terminal cysteine).

应用

Anti-Endothelin Receptor A antibody produced in rabbit is suitable for immunohistochemistry at a dilution of 1:100 using rat brain sections or rat lung paraffin embedded sections and western blotting at a dilution of 1:200 using rat brain membranes and ECL.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)

生化/生理作用

Endothelin receptor type A (ETA, ETAR) is a human G protein-coupled receptor that mediates vasoconstriction of blood vessels. It is involved in tumor cell invasion, survival and metastasis. ETAR mediates the promotion of ET-1 on colon cancer cell survival, invasion and MMP-2 expression by a PI3K-mediated mechanism. It plays a critical role in colon cancer metastasis.

外形

Lyophilized from a solution of phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 0.05% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD01092540
NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式lyophilized powder
species reactivityhuman, pig, bovine, chicken
technique(s)immunohistochemistry: 1:100 using rat brain sections or rat lung paraffin embedded sections
western blot: 1:200 using rat brain membranes and ECL
UniProt登记号P25101
运输dry ice
储存温度−20℃
Gene Informationhuman ... EDNRA(1909)
rat ... Ednra(24326)

安全信息

危险声明H412
预防措施声明P273
危险分类Aquatic Chronic 3
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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