产品说明
包装
10, 50 mg in glass bottle
生化/生理作用
NR2B selective NMDA glutamate receptor antagonist which appears to target the "polyamine site" on the NMDA receptor, setting it apart from other NR2B receptor antagonists. Possesses neuroprotective effects in models of ischemia, but prolongs the QT interval in patients; currently under investigation for acute and chronic pain.
特点和优势
This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
基本信息
| 经验(实验)分子式 | C20H23ClFNO |
| 分子量 | 347.85 |
| MDL编号 | MFCD00866651 |
| PubChem化学物质编号 | 24277709 |
| NACRES | NA.77 |
产品性质
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | white to beige |
| 溶解性 | DMSO: 5 mg/mL, clear H2O: insoluble |
| 创始人 | Sanofi Aventis |
| 储存温度 | 2-8℃ |
| SMILES string | OC(CN1CCC(CC1)Cc2ccc(F)cc2)c3ccc(Cl)cc3 |
| InChI | 1S/C20H23ClFNO/c21-18-5-3-17(4-6-18)20(24)14-23-11-9-16(10-12-23)13-15-1-7-19(22)8-2-15/h1-8,16,20,24H,9-14H2 |
| InChI key | GGUSQTSTQSHJAH-UHFFFAOYSA-N |
| Gene Information | human ... GRIN2B(2904) rat ... Adra1a(29412) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves |
Sigma-Aldrich
m.cnreagent.com
