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Proteinase 3 from human leukocytes

品牌
Sigma-Aldrich
货号
E3539
包装型号
规格纯度
≥95% (PAGE)
参考价格
10368.1 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Proteinase 3 from human leukocytes
Myeloblastin
PR3 Ag
PR-3
P29B
AGP7
产品介绍:

产品说明

一般描述

Proteinase 3 is found in high concentration in the primary granules of myeloid leukemia blasts.4

应用

Proteinase 3 has been shown to be important in the pathogenesis of human emphysema.1 It has also been used in a study to investigate the liberation of the antibacterial and cytotoxic peptide LL-37 by cleavage of human cathelicidin hCAP-183.2

生化/生理作用

Used for the detection of anti-PR3 auto-antibodies in immunoassays.
Proteinase 3 (PR-3) is a serine protease expressed in the granules of neutrophils and monocytes. Also known as myeloblastin and p29b, it degrades elastin and is associated with myeloid leukemia and Wegener′s granulomatosis.3

外形

Solution in 50 mM sodium acetate (pH 5) with 600 mM sodium chloride

基本信息

酶学委员会(EC)编号3.4.21.76 ( BRENDA | IUBMB )
MDL编号MFCD03458212
NACRESNA.54

产品性质

质量水平200
测定≥95% (PAGE)
形式buffered aqueous solution
UniProt登记号P24158
储存温度−20℃
Gene Informationhuman ... PRTN3(5657)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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