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Monoclonal Anti-Interferon-γ-Carboxyfluorescein antibody produced in mouse

品牌
Sigma-Aldrich
货号
F8648
规格纯度
clone 25723.11, purified immunoglobulin, buffered aqueous solution
参考价格
4330.86 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
Monoclonal Anti-Interferon-γ-Carboxyfluorescein antibody produced in mouse
Monoclonal Anti-Interferon-γ
产品介绍:

产品说明

一般描述

Interferons (IFNs) are cytokines that are secreted in response to viral or bacterial infections and tumorigenesis. There are two types of IFNs, type I (IFN-α and IFN-β) and type II (IFN-γ). IFN-γ binds to specific receptor complex consisting of IFNγR1 and IFNγR2. There are many pathways that are mediated by IFN-γ binding such as JAK/STAT1, AP-1, NF-κB, STAT3 and STAT5. IFN-γ is pleotropic and performs various functions related to immune response, inflammation, differentiation and activation of T cells, cell cycle and apoptosis. The most studied function of IFN-γ is priming the antigen presenting cells by up regulating major histocompatibility (MHC) Class I molecules. IFN-γ has clinical applications in autoimmune diseases (rheumatoid arthritis), multiple sclerosis, cancer, HIV and fungal infections. Anti-Interferon-γ recognizes intracellular human IFN-γ. The product is prepared by conjugation of carboxyfluorescein to Protein G purified IFN-γ monoclonal antibody.

特异性

The conjugates will identify and quantitate cells containing intracellular forms of human IFN-γ by flow cytometry.

免疫原

recombinant human IFN-γ

应用

Anti-interferon-γ antibody may be used for detection of intracellular IGN-γ in peripheral blood lymphocytes by adding 10 μL of the antibody to 1-5 X 105 cells.

外形

Solution in phosphate buffered saline containing 0.1% sodium azide.

制备说明

Purified antibody is conjugated to carboxyfluorescein.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

质量水平200
生物来源mouse
偶联物carboxyfluorescein conjugate
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆25723.11, monoclonal
形式buffered aqueous solution
species reactivityhuman
technique(s)flow cytometry: suitable
同位素/亚型IgG2b
UniProt登记号P01579
运输wet ice
储存温度2-8℃
Gene Informationhuman ... IFNG(3458)

安全信息

储存分类代码12 - Non Combustible Liquids
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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