产品说明
一般描述
Factor Va is the activated form of factor V and the cofactor of Xa. It is a component of the prothrombinase complex.
Factor V, a glycoprotein is usually seen in the alpha granules of platelets and in plasma.
生化/生理作用
Factor V is a key component in blood coagulation systems, where deficiencies can inhibit thrombin generation and affect hemostasis. It has been used in studies of coagulopathic bleeding which occurs following injury and is a leading cause of hospital deaths.
Factor Va serves as a receptor and positive effector of factor Xa. Hence it can efficiently help in the conversion of prothrombin to thrombin.
联系
View this factors role in the Coagulation Cascade
单位定义
One unit is equivalent to the Factor V activity in 1.0 mL of normal human plasma at pH 7.4 at 37 ℃.
外形
Aqueous solution containing 50% (v/v) glycerol and 5mM CaCl2
基本信息
| MDL编号 | MFCD01093755 |
| NACRES | NA.61 |
产品性质
| 质量水平 | 200 |
| 生物来源 | human |
| 形式 | solution |
| specific activity | ≥1500 units/mg protein |
| 分子量 | 168 kDa |
| technique(s) | ligand binding assay: suitable |
| UniProt登记号 | P12259 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... F5(2153) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
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