产品说明
应用
FMO5 is the only FMO isoform expressed in both adult and fetal human liver.
生化/生理作用
FMO′s are responsible for catalyzing the oxygenation of a variety of xenobiotic and drug compounds including environmental pollutants and carcinogens, which demonstrate a nucleophilic nitrogen, sulfur, selenium, and phosphorous-containing moiety associated with their respective oxides. These enzymes are classified as Phase I or oxidative drug metabolism enzymes. FMO5 is the only FMO isoform expressed in both adult and fetal human liver.
单位定义
methyl p-tolyl sulfide oxidase activity: One unit will catalyze the production of 1.0 picomole of methyl p-tolyl sulfoxide.
外形
Solution in 100 mM potassium phosphate buffer, pH 7.4.
基本信息
| 酶学委员会(EC)编号 | 1.14.13.8 ( BRENDA | IUBMB ) |
| NACRES | NA.54 |
产品性质
| 质量水平 | 200 |
| 重组 | expressed in baculovirus infected insect cells |
| 形式 | buffered aqueous solution (2.5 mg in 100 mM Potassium Phosphate Buffer) |
| specific activity | ≥700 units/mg protein |
| 分子量 | 55-60 kDa |
| 包装 | vial of 2.5 mg |
| UniProt登记号 | P49326 |
| 运输 | dry ice |
| 储存温度 | −70℃ |
| Gene Information | human ... FMO5(2330) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
Sigma-Aldrich
m.cnreagent.com
