产品说明
一般描述
CD11c is the 150 kDa (Y-chain of the leucocyte integrin complex P1 50,95. The protein belongs to a family of related heterodimeric proteins designated CD11 in the classification system for human leucocyte differentiation antigens. The CD11 family shares a common 95 kDa li-chain (CD18). In addition to the p150,95 protein, this protein family contains two other members: leucocyte function associated-1 antigen (LFA-1, CD11a) and iC3b receptor (CD11b) (Hogg, 1997). CD11c is expressed strongly on monocytes and weakly on neutrophil granulocytes (Hogg, 1997). Natural killer cells and activated B and T cells also express CD11c (Luk, 1995). Anti-CD11c, KB90, was included in the Sixth International Workshop and Conference on Human Leucocyte Differentiation Antigens, and studies by a number of laboratories confirmed its reactivity with the CD11c antigen (Hogg, 1997).
特异性
Antibody recognizes Human CD11c antigen.
免疫原
Hairy cell leukemia cells
应用
Research Sub Category
Immunoglobulins & Immunology
Milli-Mark Anti-CD11c-FITC Antibody, clone KB90 is an antibody against CD11c for use in FC.
Research Category
Inflammation & Immunology
质量
Evaluated by flow cytometry using human PBMCs
目标描述
150 kDa (Hogg, 1997)
外形
Purified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.
Protein A purified
储存及稳定性
Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.
分析说明
Control
PBMCs
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.44 |
产品性质
质量水平 | 100 |
生物来源 | mouse |
偶联物 | FITC conjugate |
抗体形式 | purified immunoglobulin |
antibody product type | primary antibodies |
克隆 | KB90, monoclonal |
species reactivity | human |
manufacturer/tradename | Milli-Mark® |
technique(s) | flow cytometry: suitable |
同位素/亚型 | IgG1κ |
NCBI登记号 | NP_000878.2 |
UniProt登记号 | P20702 |
运输 | wet ice |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich