产品说明
一般描述
LXN (latexin) is the human homologue of endogenous inhibitor of carboxypeptidase A found in rat. It was initially recognized as a neural marker in developing mammalian brain, of the lateral neocortex. This protein is composed of 222 amino acids. An α-helix links two subdomains that comprise the protein. It has high structural homology to TIG1 (tazarotene-induced gene 1).
免疫原
Recombinant latexin protein
Immunogen Sequence: GI # 9910396, sequence 1-222
应用
Anti-LXN antibody produced in chicken is suitable for indirect ELISA and western blotting.
生化/生理作用
Latexin (LXN) is a negative regulator of hematopoietic stem cell and may exert its tumor-suppressive function by altering the stem cell-like properties of melanoma cells. Its expression is reduced in human gastric cancers compared with their normal control tissues. LXN expression may have involvement in tumor suppression. It may have clinical efficacy in the treatment of malignancies.
外形
Solution in phosphate buffered saline containing 0.02% sodium azide.
产品性质
| 生物来源 | chicken |
| 质量水平 | 200 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| species reactivity | mouse, human, rat |
| manufacturer/tradename | Genway 15-288-22348F |
| technique(s) | indirect ELISA: suitable western blot: suitable |
| NCBI登记号 | NP_064554.1 |
| UniProt登记号 | Q9BS40 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... LXN(56925) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
Sigma-Aldrich
m.cnreagent.com
