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Cyanocobalamin

氰钴胺

品牌
Sigma-Aldrich
CAS
68-19-9
货号
43107
规格纯度
tested according to Ph. Eur.
参考价格
11725.5 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
68-19-9
Cyanocobalamin
Vitamin B12
α-(5,6-Dimethylbenzimidazolyl)cyanocobamide
CN-Cbl
Cyanocob(III)alamin
氰钴胺
维生素 B 12
产品介绍:

产品说明

一般描述

Cyanocobalamin, also referred to as Vitamin B12, is a water soluble vitamin.

应用

Cyanocobalamin was added in the assay buffer during the analysis step of ELISA for ensuring that all transcobalamin was saturated with cobalamin before analysis. Cyanocobalamin was also used for examining its impact on the expression of mPer1 and mPer2 in vivo.

生化/生理作用

Cyanocobalamin refers to a group of chemically-related cobalt containing molecules involved in cell processes such as DNA synthesis, fatty acid synthesis, energy production and regulation. Cyanocobalamin along with other B vitamins thiamine (B1) and pyridoxine (B6) blocks the thermal hyperalgesia in rats with neuropathic pain caused by spinal ganglia compression (CCD) or loose ligation of the sciatic nerve (CCI). It can stimulate the anaerobic biodegradation of chloroform.
Cyanocobalamin plays a role in functioning of brain and nervous system. It is also involved in hematopoiesis. Vitamin B12 deficiency leads to megaloblastic anemia. It is also associated with irreversible nervous system breakdown leading to spinal cord degeneration.

基本信息

经验(实验)分子式C63H88CoN14O14P
分子量1355.37
Beilstein4122889
EC 号200-680-0
PubChem化学物质编号329756307
NACRESNA.21

产品性质

质量水平100
生物来源fermentation/recombinant
agencyUSP/NF
tested according to Ph. Eur.
测定96.0-102.0% dry basis
形式powder
颜色dark red
溶解性water: soluble 1 gm in 80 ml
acetone: insoluble
alcohol: soluble
chloroform: insoluble
diethyl ether: insoluble
application(s)cell analysis
储存温度2-8℃
SMILES stringC/C(C1=N[C@]([C@]([C@H](CC(N)=O)[C@@]/2(C)CCC(NC[C@@H](OP([O-])(O[C@H]3[C@@H](O)[C@@H](N4C=[N]5C6=C4C=C(C)C(C)=C6)O[C@@H]3CO)=O)C)=O)([H])N([Co+]5C#N)C2=C(C)/C([C@@H](CCC(N)=O)C/7(C)C)=NC7=C/8)(C)[C@@](C)(CC(N)=O)[C@@H]1CCC(N)=O)=C9N=C8[C@@H](CCC(N)=O)[C@
InChI1S/C62H90N13O14P.CN.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;1-2;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);;/q;;+2/p-2/t31-,34-,35-,36-,37+,41-,52-,53-,56-,57?,59-,60+,61+,62+;;/m1../s1
InChI keyRMRCNWBMXRMIRW-QJRSUKKJSA-L

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 1
个人防护装备Eyeshields, Gloves, type N95 (US)

Sigma-Aldrich

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