产品说明
包装
25 mg in poly bottle
应用
Exogenous 5-fluoro-Trp is incorporated into proteins in normal protein synthesis. Since 19F is a useful reporter group, this provides a method for studying enzyme mechanisms by NMR.
生化/生理作用
5-Fluoro-Trp is nonspecifically cytotoxic. It is believed this is due to malfunctioning enzymes that have had replacements of Trp residues by 5-fluoro-Trp. However, at least one case is known where 5-fluoro-Trp substitution leads to significantly greater catalytic activity.
基本信息
| 经验(实验)分子式 | C11H11FN2O2 |
| 分子量 | 222.22 |
| Beilstein | 5052680 |
| MDL编号 | MFCD00066470 |
| eCl@ss | 32160406 |
| PubChem化学物质编号 | 57651014 |
| NACRES | NA.77 |
产品性质
| 测定 | ≥98.0% (HPLC) |
| 形式 | powder |
| 光学纯度 | enantiomeric ratio: ≥99.5:0.5 (HPLC) |
| mp | 270-280 ℃ |
| 储存温度 | 2-8℃ |
| SMILES string | N[C@@H](Cc1c[nH]c2ccc(F)cc12)C(O)=O |
| InChI | 1S/C11H11FN2O2/c12-7-1-2-10-8(4-7)6(5-14-10)3-9(13)11(15)16/h1-2,4-5,9,14H,3,13H2,(H,15,16)/t9-/m0/s1 |
| InChI key | INPQIVHQSQUEAJ-VIFPVBQESA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich
m.cnreagent.com
