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Fenoldopam mesylate

非诺多泮 甲磺酸酯

品牌
Sigma-Aldrich
CAS
67227-57-0
货号
SML0198
规格纯度
≥98% (HPLC)
参考价格
1558.18 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
67227-57-0
Fenoldopam mesylate
Fenoldopam methanesulfonate
非诺多泮 甲磺酸酯
产品介绍:

产品说明

应用

Fenoldopam mesylate may be used to study dopamine D1-mediated cell signaling.

包装

10, 50 mg in glass bottle

生化/生理作用

Fenoldopam mesylate (FM) is considered as an effective therapeutic agent to prevent the onset of postoperative AKI (PO-AKI). In healthy cats, FM can stimulate diuresis and be well-tolerated. This benzazepine-derivative is regional specific and does not cause cerebral vasodilation.
Fenoldopam mesylate is a selective dopamine D1 receptor agonist used as an antihypertensive agent. It is an agonist for D1-like dopamine receptors and binds with moderate affinity to α2-adrenoceptors. It has no significant affinity for D2-like receptors, α1 and α-adrenoceptors, 5HT1 and 5HT2 receptors, or muscarinic receptors. Fenoldopam mesylate causes peripheral vasodilation by stimulating dopamine-1receptors and α2-adrenoceptors, increasing renal blood flow.

特点和优势

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式C16H16ClNO3 · CH4O3S
分子量401.86
EC 号266-612-7
MDL编号MFCD04112986
PubChem化学物质编号329825223
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
储存条件desiccated
颜色 white to tan
mp271 ℃ (lit.)
溶解性DMSO: ≥15 mg/mL at ~60 ℃
储存温度room temp
SMILES stringCS(O)(=O)=O.Oc1ccc(cc1)C2CNCCc3c(Cl)c(O)c(O)cc23
InChI1S/C16H16ClNO3.CH4O3S/c17-15-11-5-6-18-8-13(9-1-3-10(19)4-2-9)12(11)7-14(20)16(15)21;1-5(2,3)4/h1-4,7,13,18-21H,5-6,8H2;1H3,(H,2,3,4)
InChI keyCVKUMNRCIJMVAR-UHFFFAOYSA-N
Gene Informationhuman ... DRD1(1812)

安全信息

象形图GHS07
警示用语:Warning
危险声明H302 - H317 - H319
预防措施声明P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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