GR 113808

产品名称：

144625-51-4
GR 113808
1-[2-[(Methylsulfonyl)-amino]ethyl]-4-piperidinyl]methyl 1-methyl-1H-indole-3-carboxylate

产品介绍：

产品说明

应用

GR 113808 has been used as a serotonin receptor 4 (5-HT4R) blocker to study its effects on the calcium (Ca²⁺) transients in rat ventricular cardiomyocytes. It has also been used as a 5-HT4R antagonist to study its effects on de novo enteric neurogenesis in post-embryonic zebrafish.

包装

10, 50 mg in glass bottle

生化/生理作用

GR 113808 is a 5-HT₄ serotonin receptor antagonist.

特点和优势

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

法律信息

Sold for research purposes under agreement from GlaxoSmithKline

基本信息

经验(实验)分子式	C₁₉H₂₇N₃O₄S
分子量	393.50
MDL编号	MFCD00912901
PubChem化学物质编号	24278311
NACRES	NA.77

产品性质

测定	≥98% (HPLC)
形式	solid
颜色	white to light pink
溶解性	DMSO: >20 mg/mL
创始人	GlaxoSmithKline
储存温度	2-8℃
SMILES string	Cn1cc(C(=O)OCC2CCN(CCNS(C)(=O)=O)CC2)c3ccccc13
InChI	1S/C19H27N3O4S/c1-21-13-17(16-5-3-4-6-18(16)21)19(23)26-14-15-7-10-22(11-8-15)12-9-20-27(2,24)25/h3-6,13,15,20H,7-12,14H2,1-2H3
InChI key	MOZPSIXKYJUTKI-UHFFFAOYSA-N
Gene Information	human ... HTR4(3360) rat ... Htr3a(79246), Htr4(25324)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)