Gly-Gly-His

产品名称：

7451-76-5
Gly-Gly-His
Copper-binding peptide

产品介绍：

产品说明

Amino Acid Sequence

Gly-Gly-His

一般描述

Gly-Gly-His (GGH) tripeptide with carboxyl-terminal histidine residue is hydrophilic.

应用

Gly-Gly-His has been used:

as a peptide test probe in the hydrophilic interaction liquid chromatography (HILIC) studies
in the electrochemical modification of back-side contact transducers (BSC) electrodes in copper (Cu²⁺) sensing studies
for the fabrication carbon nanotube electrode for detection of Cu²⁺ ions

生化/生理作用

Gly-Gly-His (GGH) tripeptide displays the affinity of copper (Cu²⁺) complexation. These complexes display good skin tolerance and may be useful in wound healing. GGH copper complexes are proposed to reduce tumor necrosis factor α (TNF-α)-based interleukin 6 (IL-6) secretion by in vivo studies with fibroblasts. GGH is used in comparative studies with other imidazole-containing peptides such as carnosine. An area of active application research involves the GGH binding of copper ions.

基本信息

经验(实验)分子式	C₁₀H₁₅N₅O₄
分子量	269.26
MDL编号	MFCD03452928

产品性质

测定	≥98% (TLC)
质量水平	200
形式	solid
颜色	white
储存温度	−20℃
InChI	1S/C10H15N5O4/c11-2-8(16)13-4-9(17)15-7(10(18)19)1-6-3-12-5-14-6/h3,5,7H,1-2,4,11H2,(H,12,14)(H,13,16)(H,15,17)(H,18,19)
InChI key	PDAWDNVHMUKWJR-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)