产品说明
一般描述
Glypican-3, a cell surface protein, is highly expressed in hepatocellular carcinoma (HCC) and few other human cancers including melanoma. It is a heparan sulfate proteoglycan and is present on the cell surface. Under non-reducing conditions in SDS-PAGE, the glycanated glypican 3 appears as a smear with an apparent molecular mass of 60 - 100 kDa†
生化/生理作用
Sulfate proteoglycan attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor. Regulates cell survival and inhibits cell proliferation during normal development. Potential use as marker for early disease detection.
外形
Lyophilized from a 0.2 μm filtered solution in PBS containing 50 μg of bovine serum albumin per 1 μg of cytokine.
基本信息
NACRES | NA.26 |
产品性质
质量水平 | 200 |
生物来源 | human |
重组 | expressed in NSO cells |
测定 | ≥97% (SDS-PAGE) |
形式 | lyophilized powder |
UniProt登记号 | P51654 |
储存温度 | −20℃ |
Gene Information | human ... GPC3(2719) |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich