产品说明
应用
Glycitein has been used as standard for the analysis of soy isoflavones and metabolites in urine. It has also been used to bind to recombinant estrogen and progesterone receptors to know the relative binding affinity (RBA) for detection of potential endocrine disruptors.
包装
10 mg in glass insert
生化/生理作用
Glycitein is a soybean (yellow cultivar) isoflavonoid; its natural glycosides are synergistic with genistein in inducing specific gene expression. Glycitein may be used to study anti-oxidation processes at the level of gene transcription where it increases the binding of transcription factors [nuclear factor-E2-related factor 2 (Nrf2) and c-Jun] to the antioxidant response element (ARE) on HO-1 and NQO1 promoters. Glycitein may be used in combination with other isoflavonoids such as genistein and daidzein to study apoptosis.
Glycitein possesses weak estrogenic activity than other soy isoflavones.
基本信息
| 经验(实验)分子式 | C16H12O5 |
| 分子量 | 284.26 |
| MDL编号 | MFCD00016679 |
| PubChem化学物质编号 | 329799906 |
| NACRES | NA.51 |
产品性质
| 生物来源 | synthetic (organic) |
| 质量水平 | 100 |
| 测定 | ≥97% (HPLC) |
| 形式 | powder |
| 溶解性 | DMF: 1 mg/mL, clear, colorless to faintly yellow |
| 储存温度 | −20℃ |
| SMILES string | COc1cc2C(=O)C(=COc2cc1O)c3ccc(O)cc3 |
| InChI | 1S/C16H12O5/c1-20-15-6-11-14(7-13(15)18)21-8-12(16(11)19)9-2-4-10(17)5-3-9/h2-8,17-18H,1H3 |
| InChI key | DXYUAIFZCFRPTH-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich
m.cnreagent.com
