氯化乙酰胆碱

产品名称：

60-31-1
Acetylcholine Chloride
ACh
氯化乙酰胆碱

产品介绍：

产品说明

一般描述

Acetylcholine is a neurotransmitter released at nerve endings in both the central and peripheral nervous systems. Acetylcholine chloride (C7H16ClNO2) is a stable cholinergic agonist with muscarinic and nicotinic actions. It is available as white or off-white hygroscopic crystals, or as a crystalline powder. Acetylcholine chloride is hygroscopic in nature and is highly soluble in water, alcohol, propylene glycol and chloroform.

应用

Acetylcholine chloride has been used:

as an agent to trigger sudomotor axon reflex response during autonomic test
to induce contraction amplitude of pyloric circular smooth muscle strip (PCSMS) in rats
as a substrate for acetylcholinesterase
to stimulate after discharge in Aplysia bag cell neurons

生化/生理作用

氯化乙酰胆碱，20mg/kg体重注射，减少小鼠实验性诱发脓毒病的死亡和血浆促炎细胞因子。类胆碱能抗-炎症机制可能通过乙酰胆碱和 α7n单核细胞，巨噬细胞和中性粒细胞上的胆红素受体互作接待，降低了促炎细胞活素，比如 TNF-α,IL-1β,和IL-6。

注意

非常吸湿

法律信息

Redi-Dri is a trademark of sigma-aldrich Co. LLC

基本信息

线性分子式	(CH₃)₃N⁺CH₂CH₂OCOCH₃Cl^-
分子量	181.66
Beilstein	3571875
MDL编号	MFCD00011698

产品性质

产品线	Redi-Dri^™
质量水平	100
测定	≥99% (TLC)
质量	free-flowing
mp	146-150 ℃ (lit.)
溶解性	H₂O: 100 mg/mL
SMILES string	[Cl-].CC(=O)OCC[N+](C)(C)C
InChI	1S/C7H16NO2.ClH/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1
InChI key	JUGOREOARAHOCO-UHFFFAOYSA-M

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable