产品说明
应用
This polymer is a amphiphilic diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PLGA block. This biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). Additionally, well-defined nanoparticles with tunable size and properties can be prepared by altering the molecular weight ratios between hydrophilic and hydrophobic blocks, as well as by controlling formulation parameters.
基本信息
| 线性分子式 | H[(C3H4O2)x(C2H2O2)y]mO[C2H4O]nCH3 |
产品性质
| 形式 | powder |
| 投料比 | lactide:glycolide 80:20 |
| 分子量 | PEG average Mn 5,000 (by NMR) PLGA average Mn 5,000 (by NMR) |
| 杂质 | ≤500 ppm (GC) |
| 颜色 | white |
| 储存温度 | −20℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
