产品说明
一般描述
Chemical structure: pyrimidine
应用
Tioconazole was used to study the synergistic mechanisms of antifungals on Candida albicans as well as significant drug-drug interactions in vivo.
生化/生理作用
Tioconazole is an antifungal medication of the imidazole class used to treat infections caused by fungus and yeast.It is more active than fluconazole or voriconazole against Candida glabrata mutant strains. It acts by membrane disruption and loss of intracellular ATP.
包装
10G
其他说明
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 03907.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.
基本信息
| 经验(实验)分子式 | C16H13Cl3N2OS |
| 分子量 | 387.71 |
| EC 号 | 265-973-8 |
| MDL编号 | MFCD00057276 |
| PubChem化学物质编号 | 329747834 |
| NACRES | NA.85 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥96.5% (HPLC) 96.5-103.5% (NT) 97% |
| 形式 | powder |
| 颜色 | white to off-white |
| 作用机制 | cell membrane | interferes |
| 抗生素抗菌谱 | fungi yeast |
| SMILES string | Clc1ccc(C(Cn2ccnc2)OCc3ccsc3Cl)c(Cl)c1 |
| InChI | 1S/C16H13Cl3N2OS/c17-12-1-2-13(14(18)7-12)15(8-21-5-4-20-10-21)22-9-11-3-6-23-16(11)19/h1-7,10,15H,8-9H2 |
| InChI key | QXHHHPZILQDDPS-UHFFFAOYSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H302 |
| 危险分类 | Acute Tox. 4 Oral |
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
Sigma-Aldrich
m.cnreagent.com
