产品说明
生化/生理作用
Growth factor ligand for ErbB3 and ErbB4 receptor tyrosine kinases. The binding of HRG results in receptor dimerization and receptor trans-autophosphorylation. The phosphorylated receptors recruit cellular signaling proteins, initiating signaling pathways.
分析说明
The biological activity is measured by its ability to stimulate the proliferation of human MCF-7 cells grown under serum-free conditions.
基本信息
| MDL编号 | MFCD03457066 |
| NACRES | NA.32 |
产品性质
| 质量水平 | 200 |
| 生物来源 | human |
| 重组 | expressed in E. coli |
| 测定 | ≥98% (SDS-PAGE) |
| 形式 | lyophilized powder |
| 效能 | <0.50 ng/mL |
| 分子量 | predicted mol wt 8 kDa |
| 包装 | pkg of 10 and 50 μg |
| 储存条件 | avoid repeated freeze/thaw cycles |
| 杂质 | endotoxin, tested |
| 颜色 | white |
| UniProt登记号 | Q02297 |
| 储存温度 | −20℃ |
| Gene Information | human ... NRG1(3084) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich
m.cnreagent.com
