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Heregulin-β, EGF Domain human

品牌
Sigma-Aldrich
货号
H0786
规格纯度
≥80% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous glycerol solution
参考价格
9015.14 *本价格含增值税费
促销
服务
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数量
-+
产品名称:
Heregulin-β, EGF Domain human
HRG-β
产品介绍:

产品说明

一般描述

Truncated human sequence (amino acids 178-241) corresponding to the EGF domain and purified as a GST-fusion protein, cleaved with thrombin.

生化/生理作用

Growth factor ligand for ErbB3 and ErbB4 receptor tyrosine kinases. The binding of HRG results in receptor dimerization and receptor trans-autophosphorylation. The phosphorylated receptors recruit cellular signaling proteins, initiating signaling pathways.

外形

Solution in phosphate buffered saline containing 30% glycerol.

分析说明

Stimulates tyrosine phosphorylation of the ErbB-3/HER-3 receptor.
The biological activity is measured by its ability to activate the c-ErbB3/HER-3 receptor in treated MCF-7 cells.

基本信息

MDL编号MFCD01867052
NACRESNA.32

产品性质

质量水平200
生物来源human
重组expressed in E. coli
测定≥80% (SDS-PAGE)
形式buffered aqueous glycerol solution
分子量 185 kDa
包装pkg of 100 μg
储存条件avoid repeated freeze/thaw cycles
UniProt登记号Q02297
运输dry ice
储存温度−20℃
Gene Informationhuman ... NRG1(3084)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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