产品说明
一般描述
Homeobox C8 (HOXC8) is a member of homeobox (HOX) family. It is a transcription factor, expressed in neural tube, brain, breast and adult bone marrow. HOX genes consist of a highly conserved 60-amino-acid region (the homeobox) with DNA-binding activity, that contributes to their activity as transcription factors. The gene is located on human chromosome 12q13.
免疫原
synthetic peptide corresponding to amino acids 96-110 of human HOXC8 conjugated to KLH. The corresponding sequence is identical in mouse and rat.
应用
Anti-HOXC8 antibody produced in rabbit has been used in immunoblotting and immunoprecipitation.
生化/生理作用
Homeobox C8 (HOXC8) is involved in cell growth, migration and metastasis of various cancers. Hox genes are important for embryonic development. Mutations in this gene are implicated in the development of cancers, such as leukemias or neoplasms of the breast, prostate, kidney, colon, skin and brain.
外形
0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 200 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen ~34 kDa |
| species reactivity | human |
| 浓度 | ~1.0 mg/mL |
| technique(s) | immunoprecipitation (IP): 2.5-5 μg using lysates of HEK-293T cells over expressing human HOXC8 western blot: 1-2 μg/mL using extracts of HEK-293T cells over expressing human HOXC8 |
| UniProt登记号 | P31273 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... HOXC8(3224) mouse ... Hoxc8(15426) rat ... Hoxc8(24460) |
Sigma-Aldrich
m.cnreagent.com
