产品说明
一般描述
HIPK4 (homeodomain-interacting protein kinase 4) is present in the lungs and white adipose tissues. The protein mainly localizes in the cytoplasm. However, a weak signal is also present in the nucleus.
生化/生理作用
HIPK4 (homeodomain-interacting protein kinase 4) is serine/threonine kinase protein. HIPK4-mediated phosphorylation of p53 is crucial for p53-associated transcriptional repression.
外形
Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.
法律信息
PRECISIO is a registered trademark of sigma-aldrich Co. LLC
基本信息
NACRES | NA.32 |
产品性质
质量水平 | 200 |
重组 | expressed in baculovirus infected Sf9 cells |
产品线 | PRECISIO® Kinase |
测定 | ≥70% (SDS-PAGE) |
形式 | buffered aqueous glycerol solution |
specific activity | 172-232 nmol/min·mg |
分子量 | ~110 kDa |
UniProt登记号 | Q8NE63 |
运输 | dry ice |
储存温度 | −70℃ |
Gene Information | human ... HIPK4(147746) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich