产品说明
免疫原
synthetic peptide corresponding to amino acids 31-46 of human IL-22 recptor precursor.
生化/生理作用
Interleukin-22 (IL-22) belongs to the IL-10 family of T-cell associated cytokines, highly expressed by Th17 cell subset and also by cells of innate immunity system. The cellular effects of IL-22 are mediated by a heterodimeric receptor made up of IL-22 and IL-10Rβ. IL-22 signaling mediates proliferation of epithelial cells during inflammation mainly by the activation of STAT1 and STAT3 signaling.
特点和优势
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外形
Solution in phosphate buffered saline containing 0.02% sodium azide.
基本信息
| MDL编号 | MFCD04040433 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 200 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen ~62 kDa |
| species reactivity | human |
| 浓度 | ~1 mg/mL |
| technique(s) | ELISA: suitable immunocytochemistry: suitable immunofluorescence: suitable immunohistochemistry: suitable western blot: suitable |
| UniProt登记号 | Q8N6P7 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... IL22RA1(58985) |
Sigma-Aldrich
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