产品说明
一般描述
IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine. Recombinant murine IL-3 is a 15.1 kDa globular protein containing 135 amino acid residues.
生化/生理作用
IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Recombinant murine IL-3 is a 15.1 kDa globular protein containing 135 amino acid residues.
重悬
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8℃ for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a stabilizer (example 5% Trehalose) and store in working aliquots at -20℃ to -80℃.
基本信息
MDL编号 | MFCD00164817 |
NACRES | NA.32 |
产品性质
质量水平 | 200 |
生物来源 | mouse |
重组 | expressed in E. coli |
测定 | ≥98% (SDS-PAGE) |
形式 | lyophilized |
分子量 | 15.1 kDa |
包装 | pkg of 10 μg |
technique(s) | cell culture | mammalian: suitable |
杂质 | <0.1 EU/μg endotoxin, tested |
颜色 | white |
UniProt登记号 | P01586 |
运输 | dry ice |
储存温度 | −20℃ |
Gene Information | mouse ... IL3(16187) |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich