产品说明
生化/生理作用
Interleukin 18, also known as interferon-γ-inducing factor (IGIF) and IL-1γ, is a proinflammatory cytokine. It is an inducer of IFN-γ and Th1 (T cell helper type 1) responses (cell differentiation, cell-mediated cytotoxicity and inflammation). IL-18 induces the migration of microvascular endothelial cells.
外形
Lyophilized from 20 mM Tris , 500 mM NaCl, 0.5 mM EDTA, 1 mM TCEP, 0.05% (w/v) PEG8000 pH 8.0 with 5% Trehalose,and 50 μg BSA per μg IL-18
分析说明
The biological activity is measured by its ability to induce mouse IFN-γ production by activated mouse T cells.
基本信息
MDL编号 | MFCD01867247 |
NACRES | NA.32 |
产品性质
质量水平 | 200 |
生物来源 | rat |
重组 | expressed in E. coli |
测定 | >97% (SDS-PAGE) |
形式 | lyophilized powder |
效能 | 3-6 ng/mL ED50 |
分子量 | predicted mol wt ~18.4 kDa |
包装 | pkg of 25 μg |
杂质 | endotoxin, tested |
UniProt登记号 | Q16552 |
运输 | dry ice |
储存温度 | −20℃ |
Gene Information | rat ... Il18(29197) |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich