产品说明
一般描述
The gene KLK11 (kallikrein 11) encodes a member of the kallikrein gene family. The gene is mapped to human chromosome 19q13.4. It is found to be highly expressed in the prostate. It has been found to be present in biological fluids and in serum of patients with various cancers. KLK11 is also found to be expressed in stomach, trachea, skin, and colon.
免疫原
synthetic peptide corresponding to residues 68-82 of the human Kallikrein 11. This sequence is 86% identical in mouse and rat.
生化/生理作用
The gene KLK11 (kallikrein 11) encodes a putative serine protease that is overexpressed in prostate and ovarian cancer. It serves as a biomarker for prognosis of ovarian cancer. It can serve as a marker for distinguishing between prostate cancer and benign prostatic hyperplasia.
外形
solution in phosphate buffered saline, containing 0.02% sodium azide.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 200 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen ~35 kDa |
| species reactivity | mouse, human, rat |
| 浓度 | ~1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: 1:500-1:1,000 |
| UniProt登记号 | Q9UBX7 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... KLK11(11012) mouse ... Klk11(56538) rat ... Klk11(292849) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
Sigma-Aldrich
m.cnreagent.com
