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PKCθ, active, GST tagged human

品牌
Sigma-Aldrich
货号
K4643
规格纯度
PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
参考价格
4449.75 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
PKCθ, active, GST tagged human
MGC141919
PRKCQ
nPKC-theta
PRKCT
MGC126514
产品介绍:

产品说明

一般描述

PKCθ (protein kinase C θ) is a serine/threonine kinase, belonging to protein kinase C family.

生化/生理作用

PKCθ (protein kinase C θ) is required for T cell activation and proliferation. In presence of TCR (T cell receptor) stimulation, it is responsible for activation of NF-AT (nuclear factor of activated T-cells), NF-κB (nuclear factor κ B) and AP1 (adaptor-related protein complex 1). It might be a target for the treatment of type 2 diabetes. PKCθ is needed for fat-mediated insulin resistance in skeletal muscle.

外形

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

法律信息

PRECISIO is a registered trademark of sigma-aldrich Co. LLC

基本信息

NACRESNA.32

产品性质

质量水平200
重组expressed in baculovirus infected Sf9 cells
产品线PRECISIO® Kinase
测定≥70% (SDS-PAGE)
形式buffered aqueous glycerol solution
specific activity673-911 nmol/min·mg
分子量 ~110 kDa
UniProt登记号Q04759
运输dry ice
储存温度−70℃
Gene Informationhuman ... PRKCQ(5588)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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