产品说明
应用
MAPTrix™ Technology provides a true extracellular microenvironment (ECM) by presenting combinatorial peptide motifs. The ECM, defined by biochemical cues and physical cues, is a deciding factor in a wide range of cellular processes including cell adhesion, proliferation, differentiation, and expression of phenotype-specific functions.Currently existing technology offers simple and merely adequate environments that facilitate simple cell processes such as cellular adhesion. The simple presentation of cell adhesion motifs is not optimal for controlling more integrated processes. Crosstalk among signaling pathways act synergistically to enhance cellular responses such as cell adhesion or proliferation. A study showed that a combination of extracellular matrix derived peptides presented on a surface may enhance cell adhesion strength and focal adhesion assembly. The combinatorial presentation of ECM peptides on cell growth surfaces may also promote elevated proliferation rates of primary or stem cells.
特点和优势
法律信息
MAPTrix is a trademark of Kollodis Biosciences
基本信息
NACRES | NA.75 |
产品性质
无菌性 | Filtered sterilized solution |
形式 | aqueous solution |
分子量 | ~23.2 kDa |
包装 | pkg of 10 mg |
浓度 | 1.0 mg/mL protein |
technique(s) | cell culture | mammalian: suitable |
结合特异性 | Receptor: α5β1 Domain: FNIII-9 Binding Motif: PHSRN |
运输 | ambient |
储存温度 | 2-8℃ |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich