LWH-63 hydrochloride

产品名称：

276890-57-4
LWH-63 hydrochloride
NIH-3
4-(N-Ethyl-n-4-hydroxybutyl)amino-2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)pyrrolo[2,3-d]pyrimidine hydrochloride

产品介绍：

产品说明

生化/生理作用

Non-peptide CRF₁ corticotrophin-releasing factor antagonist. K_i = 0.68 nM; blocks ethanol-induced effects as well as CRF effects in mice, suggesting a possible therapeutic target for the treatment of stress-induced alcohol drinking.

基本信息

经验(实验)分子式	C₂₄H₃₅ClN₄O
分子量	431.01
MDL编号	MFCD07784506
PubChem化学物质编号	24724529
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	solid
颜色	light brown
溶解性	DMSO: ~10 mg/mL H₂O: insoluble
储存温度	2-8℃
SMILES string	Cl[H].CCN(CCCCO)c1nc(C)nc2n(c(C)c(C)c12)-c3c(C)cc(C)cc3C
InChI	1S/C24H34N4O.ClH/c1-8-27(11-9-10-12-29)23-21-18(5)19(6)28(24(21)26-20(7)25-23)22-16(3)13-15(2)14-17(22)4;/h13-14,29H,8-12H2,1-7H3;1H
InChI key	DKVWSJKPRJIFPC-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)