N-γ-Maleimidobutyryloxysuccinimide

产品名称：

80307-12-6
GMBS
N-γ-Maleimidobutyryloxysuccinimide

产品介绍：

产品说明

一般描述

Heterobifunctional reagent useful for preparation of conjugates such as secondary antibodies and β-galactosidase for EIA procedures or for immobilizing enzymes on solid supports.
N-γ-maleimidobutyryloxysuccinimide ester (GMBS) is an aliphatic crosslinker for immunotoxins (IT).(1) It is used for the generation of conjugated Poly-γ-D-glutamic acid.

应用

GMBS is suitable for use:

as a hetero-bifunctional cross-linking reagent for the immobilization of neural adhesion molecule L1 onto silicon dioxide surface
for the crosslinking of biochips with functionalized gold nanoparticles
for coating salinized capillary tube prior to neutravidin treatment in biosensor sandwich immunoassay

警告

Toxicity: Irritant (B)

重悬

Reconstitute to 10 mg/ml in tetrahydrofuran or DMSO. Add 1 ml of this stock solution dropwise, with stirring, to 10 ml of 20 mM phosphate buffer.

其他说明

Rusin, K.M., et al. 1992. Biosens. Bioelectron. 7, 367.
Kitagawa, T., et al. 1983. J. Biochem. 94, 1160.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C₁₂H₁₂N₂O₆
分子量	280.23
MDL编号	MFCD00036817

产品性质

测定	≥90% (HPLC)
质量水平	100
形式	solid
manufacturer/tradename	Calbiochem^®
储存条件	OK to freeze
储存温度	−20℃
InChI	1S/C12H12N2O6/c15-8-3-4-9(16)13(8)7-1-2-12(19)20-14-10(17)5-6-11(14)18/h3-4H,1-2,5-7H2
InChI key	PVGATNRYUYNBHO-UHFFFAOYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable