产品说明
一般描述
Product Source: Expressed by baculovirus in Sf21 insect cells.
N-terminal 6His-tagged, recombinant, human Src, amino acids 1-530, expressed by baculovirus in Sf21 insect cells.
The mutant form of Src (Src, 1-530) has been identified in cases of advanced colon cancer. This truncating mutation generates an open active form of Src that has been found to be transforming, tumorigenic and metastasis promoting.
应用
Research Category
Metabolism
Research Sub Category
Cardiovascular Disease
Metabolic Disorders
生化/生理作用
Target Sub-Family: TK
Protein Target: Src
包装
Also available in 10 μg size (cat#14-746) and in bulk (cat# 14-746-K).
外形
50mM Tris-HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution
Ni2+/NTA-agarose
储存及稳定性
6 months at -70°C from date of shipment.
其他说明
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
法律信息
GenBank is a registered trademark of United States Department of Health and Human Services
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160405 |
NACRES | NA.32 |
产品性质
质量水平 | 100 |
生物来源 | human |
分子量 | Mw 61.7 kDa |
manufacturer/tradename | Upstate® |
technique(s) | activity assay: suitable (kinase) |
GenBank® accession no. | K03218 |
UniProt登记号 | P05480 (mouse) P12931 Q9WUD9 (rat) |
Gene Information | human ... SRC(6714) |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H317 |
预防措施声明 | P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364 |
危险分类 | Skin Sens. 1 |
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich