产品说明
一般描述
Methiothepin belongs to a new class of dibenzothiophenes. Methiothepin possesses neuroleptic activity.
应用
Methiothepin mesylate salt has been used to explore the relationship between circulating cells and the niche. It has also been used in serotonin (5-HT) and antagonists in vivo bioassays and in in vivo antagonist and lipopolysaccharide stimulations.
包装
100, 250 mg in glass bottle
生化/生理作用
Methiothepin mesylate salt is a 5-HT1, 5-HT6, 5-HT7 serotonin receptor antagonist, which blocks serotonin autoreceptors.
基本信息
线性分子式 | C20H24N2S2 · CH3SO3H |
分子量 | 452.65 |
MDL编号 | MFCD00153831 |
PubChem化学物质编号 | 24278104 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | solid |
储存条件 | desiccated |
颜色 | white |
溶解性 | H2O: 13 mg/mL |
SMILES string | CS(O)(=O)=O.CSc1ccc2Sc3ccccc3CC(N4CCN(C)CC4)c2c1 |
InChI | 1S/C20H24N2S2.CH4O3S/c1-21-9-11-22(12-10-21)18-13-15-5-3-4-6-19(15)24-20-8-7-16(23-2)14-17(18)20;1-5(2,3)4/h3-8,14,18H,9-13H2,1-2H3;1H3,(H,2,3,4) |
InChI key | CZMDZGZYKOGLJY-UHFFFAOYSA-N |
Gene Information | human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR6(3362), HTR7(3363) |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich