产品说明
特异性
Binds to the main immunogenic region on the extracellular surface of the α1 subunit of muscle AChR′s and to homologous regions on α3 and α5 subunits of neuronal AChR′s. The epitope is located on the extracellular surface of the α1 subunit of the muscle nicotinic acetylcholine receptor. The antibody binds to denatured chick α5 AChR, but does not bind well to denatured α3, α4, α7, α8, and β2. It may also bind β3 due to homology of main immunogenic region. May be used to localize and detect the α1, α3 and α5 subunits of the nicotinic acetylcholine receptor (AChR).
免疫原
nicotinic acetylcholine receptor from the electric eel Electrophorus.
外形
Solution in 20 mM Na3PO4, pH 7.2, containing 150 mM NaCl and 0.05 % sodium azide.
法律信息
Sold with permission of the Salk Institute
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
MDL编号 | MFCD00677279 |
产品性质
质量水平 | 100 |
生物来源 | rat |
偶联物 | unconjugated |
抗体形式 | purified immunoglobulin |
antibody product type | primary antibodies |
克隆 | mAb 35, monoclonal |
形式 | buffered aqueous solution |
species reactivity | eel, chicken, human |
should not react with | Xenopus |
technique(s) | immunohistochemistry (frozen sections): 1:3,000 |
同位素/亚型 | IgG1 |
UniProt登记号 | CHRNA1 |
运输 | dry ice |
储存温度 | −20℃ |
Gene Information | human ... CHRNA1(1134), CHRNA3(1136), CHRNA5(1138) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
Sigma-Aldrich