产品说明
一般描述
MO25 is a 40 kDa scaffolding protein that interacts with STRADα and LKB1 to regulate tumor suppression. MO25 also facilitates the activation and cytoplasmic localization of LKB1 . Anti-MO25 (C-terminus) antibody detects human MO25 (approx. 40 kDa). The product is also predicted to react with rat and mouse MO25. Staining of the MO25 band in immunoblotting is specifically inhibited by the immunizing peptide.
免疫原
synthetic peptide corresponding to amino acids 323-341 located near the C-terminus of human MO25. This sequence is identical in chicken, dog, and bovine MO25 and highly conserved in rat and mouse MO25 (2 amino acid substitutions).
应用
Anti-MO25 (C-terminus) antibody is suitable for use in western blot (0.5-1 μg/mL using HEK-293T cells expressing human MO25 and in PC12 cell lysates).
外形
Solution in 0.01 M phosphate buffered saline, pH 7.4, and 15 mM sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
NACRES | NA.44 |
产品性质
生物来源 | rabbit |
质量水平 | 200 |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | antigen ~40 kDa |
species reactivity | rat (predicted), mouse (predicted), human |
包装 | antibody small pack of 25 μL |
增强验证 | recombinant expression Learn more about Antibody Enhanced Validation |
浓度 | ~2 mg/mL |
technique(s) | western blot: 0.5-1 μg/mL using HEK-293T cells expressing human MO25 and PC12 cell lysates |
UniProt登记号 | Q9Y376 |
运输 | dry ice |
储存温度 | −20℃ |
Gene Information | human ... CAB39(51719) mouse ... Cab39(12283) rat ... Cab39(301574) |
Sigma-Aldrich