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Anti-Matrix Metalloproteinase-25, Propeptide Region antibody produced in rabbit

品牌
Sigma-Aldrich
货号
M5067
规格纯度
~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution
参考价格
4330.86 *本价格含增值税费
促销
服务
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  • 增值税票
数量
-+
产品名称:
Anti-Matrix Metalloproteinase-25, Propeptide Region antibody produced in rabbit
Anti-MT6-MMP
Anti-MMP-25
产品介绍:

产品说明

一般描述

Matrix metalloproteinase-25 (MMP-25) belongs to the membrane-anchored matrix metalloproteinase subfamily. It is produced as a 57-60kDa monomer and is later expressed as a homodimer of 120kDa. This glycophosphatidylinositol (GPI)-anchored metalloproteinase is expressed in the polymorphonuclear neutrophils. MMP-25 possesses an extracellular prodomain along with other functional domains. The gene encoding it is localized on human chromosome 16p13.3.

特异性

By immunoblotting against the reduced protein, the antibody identifies a band at 65 kDa as well as breakdown products. The antibody recognizes the zymogen and not activated forms of the enzyme.

免疫原

synthetic peptide corresponding to the propeptide region of human matrix metalloproteinase-25 (membrane-type matrix metalloproteinase-6).

生化/生理作用

Matrix metalloproteinase-25 (MMP-25) acts as a marker for chronic respiratory diseases. Studies have indicated that MMP-25 can degrade fibrin, fibronectin, gelatin and type IV collagen. It may have a role in the degradation of the pericellular extracellular matrix.

外形

Solution in 0.01 M phosphate buffered saline containing 50% glycerol and 0.05% sodium azide.

基本信息

MDL编号MFCD04974754
NACRESNA.41

产品性质

生物来源rabbit
质量水平200
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous glycerol solution
species reactivityhuman, mouse
浓度~1 mg/mL
technique(s)western blot: 1:1,000
UniProt登记号Q9NPA2
运输wet ice
储存温度−20℃
Gene Informationhuman ... MMP25(64386)
mouse ... Mmp25(240047)

Sigma-Aldrich

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