Anti-Matrix Metalloproteinase-26, N-Terminal Active antibody produced in rabbit

产品说明

一般描述

Matrix metalloproteinase-26 (MMP-26) is also known as matrilysin-2 and endometase. It is expressed in normal tissues and also in human carcinoma cells. MMP-26 possesses a propeptide domain, a signal peptide and a catalytic domain but does not have the hemopexin-like domain which is common to other members of its family. The MMP-26 gene is localized to chromosome 11p15.3.

特异性

By immunoblotting against the reduced protein, the antibody identifies bands at 30 kDa and 18 kDa (zymogen and active MMP-26, respectively).

免疫原

synthetic peptide corresponding to the N-terminal of active human matrix metalloproteinase-26.

生化/生理作用

Matrix metalloproteinase-26 (MMP-26) degrades fibronectin, type IV collagen and activated pro-metalloproteinase-9. MMP-26 also aids in development of tumors.

外形

Solution in 0.01 M phosphate buffered saline containing 50% glycerol and 0.05% sodium azide.

基本信息

产品性质