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Meloxicam sodium salt hydrate

品牌
Sigma-Aldrich
CAS
71125-39-8
货号
M3935
包装型号
规格纯度
≥98% (HPLC)
参考价格
2684.1 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
71125-39-8
Meloxicam sodium salt hydrate
4-Hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide sodium hydrate
Metacam sodium salt hydrate
UH-AC 62XX sodium salt hydrate
Mobec sodium salt hydrate
产品介绍:

产品说明

应用

Meloxicam sodium salt hydrate has been used:

  • as a cyclooxygenase-2 (COX-2) inhibitor in solid Ehrlich tumor
  • as an alternative to diclofenac nonsteroidal anti-inflammatory drugs (NSAID) to treat vultures
  • as a reference standard in liquid chromatography electrospray ionisation mass spectrometry (LC-ESI/MS)
  • to test its effect on prostaglandin (PGE2) production in lipopolysaccharide (LPS)-induced COX-2 protein expression in RAW246.7 cells

包装

100 mg in glass bottle

生化/生理作用

Meloxicam, a member of the oxicam family, is a non-steroidal anti-inflammatory drug (NSAID). It is synthesized from piroxicam with aryl and the pyridyl ring substitution. Meloxicam is a cyclooxygenase-2 (COX-2) inhibitor, it may be useful in treating inflammation and pain. Meloxicam has been shown to stop thymulin-induced increas in concentration of cytokines and Nerve growth factor (NGF) in the liver of rats. Meloxicam also suppresses tumor growth and may be capable of antagonizing cachexia in vitro. It promotes apoptosis in hepatocellular carcinoma.

特点和优势

This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

基本信息

经验(实验)分子式C14H12N3NaO4S2 · xH2O
分子量373.38 (anhydrous basis)
MDL编号MFCD11046047
PubChem化学物质编号24278802
NACRESNA.77

产品性质

测定≥98% (HPLC)
形式powder
颜色light yellow to dark yellow
溶解性DMSO: 5 mg/mL, clear
创始人Boehringer Ingelheim
储存温度room temp
SMILES stringO.[Na+].CN1C(C(=O)Nc2ncc(C)s2)=C([O-])c3ccccc3S1(=O)=O
InChI1S/C14H13N3O4S2.Na.H2O/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10(9)23(20,21)17(11)2;;/h3-7,18H,1-2H3,(H,15,16,19);;1H2/q;+1;/p-1
InChI keyIZBZAOZGNNQKPJ-UHFFFAOYSA-M
Gene Informationhuman ... PTGS2(5743)

安全信息

象形图GHS06
警示用语:Danger
危险声明H301 - H315 - H319 - H335
预防措施声明P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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