产品说明
应用
Meloxicam sodium salt hydrate has been used:
包装
100 mg in glass bottle
生化/生理作用
Meloxicam, a member of the oxicam family, is a non-steroidal anti-inflammatory drug (NSAID). It is synthesized from piroxicam with aryl and the pyridyl ring substitution. Meloxicam is a cyclooxygenase-2 (COX-2) inhibitor, it may be useful in treating inflammation and pain. Meloxicam has been shown to stop thymulin-induced increas in concentration of cytokines and Nerve growth factor (NGF) in the liver of rats. Meloxicam also suppresses tumor growth and may be capable of antagonizing cachexia in vitro. It promotes apoptosis in hepatocellular carcinoma.
特点和优势
This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
基本信息
经验(实验)分子式 | C14H12N3NaO4S2 · xH2O |
分子量 | 373.38 (anhydrous basis) |
MDL编号 | MFCD11046047 |
PubChem化学物质编号 | 24278802 |
NACRES | NA.77 |
产品性质
测定 | ≥98% (HPLC) |
形式 | powder |
颜色 | light yellow to dark yellow |
溶解性 | DMSO: 5 mg/mL, clear |
创始人 | Boehringer Ingelheim |
储存温度 | room temp |
SMILES string | O.[Na+].CN1C(C(=O)Nc2ncc(C)s2)=C([O-])c3ccccc3S1(=O)=O |
InChI | 1S/C14H13N3O4S2.Na.H2O/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10(9)23(20,21)17(11)2;;/h3-7,18H,1-2H3,(H,15,16,19);;1H2/q;+1;/p-1 |
InChI key | IZBZAOZGNNQKPJ-UHFFFAOYSA-M |
Gene Information | human ... PTGS2(5743) |
安全信息
象形图 | |
警示用语: | Danger |
危险声明 | H301 - H315 - H319 - H335 |
预防措施声明 | P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338 |
危险分类 | Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
靶器官 | Respiratory system |
储存分类代码 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich