产品说明
一般描述
NOTCH homolog-2 (NOTCH2) is part of the NOTCH signaling pathway and the gene encoding it is localized on chromosome 1p13-p11.
免疫原
synthetic peptide corresponding to residues 1718-1733 of human NOTCH2. This sequence is 93% identical in mouse and rat.
生化/生理作用
NOTCH homolog-2 (NOTCH2) is a stimulator of metaplasia in goblet cells, which is seen in respiratory diseases like asthma. Mutations in the NOTCH2 gene are associated with Hajdu-Cheney syndrome.
外形
solution in phosphate buffered saline, containing 0.02% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 200 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen ~230 kDa (extracellular) antigen ~280 kDa |
| species reactivity | human |
| 浓度 | ~1 mg/mL |
| technique(s) | western blot: 1:500-1:1,000 |
| UniProt登记号 | Q04721 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... NOTCH2(4853) mouse ... Notch2(18129) rat ... Notch2(29492) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
Sigma-Aldrich
m.cnreagent.com
