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Rat Epidermal Keratinocytes: REK, neonatal

品牌
Sigma-Aldrich
货号
R102-05N
包装型号
规格纯度
参考价格
7464.78 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
Rat Epidermal Keratinocytes: REK, neonatal
产品介绍:

产品说明

一般描述

REK from Cell Applications, Inc. provide a suitable model system to study many aspects of epithelial function and disease, particularly those related to skin biology and toxicology. It was shown that TGFβ1 treatment decreased c-Myc mRNA in REK which, taken together with the TGFβ1-induced growth arrest exhibited by keratinocytes and opposite results obtained in other cells, suggests a correlation between c-Myc mRNA expression and the mitogenic response (Nakai, 2008). Additionally, REK were used to demonstrate that pathological increases in keratinocyte sodium channels Nav1.1, Nav1.6, and Nav1.8 expression may contribute to pain by increasing epidermal ATP release, resulting in excessive activation of P2X receptors on primary sensory axons (Zhao, 2008). REK were also used to demonstrate that laminin 332 deposition is inhibited by ionizing radiation and, in combination with slower keratinocyte migration, can contribute to the delayed wound healing of irradiated skin (Jourdan, 2011).

细胞系来源

Skin

应用

Skin biology and toxicology, wound healing, artificial skin, cell proliferation, migration, UV light response.

组分

Rat Keratinocyte Basal Medium that contains 10% FBS and 10% DMSO

质量

Each lot was tested for proper morphology, Population Doublings, Negative for HIV, Hepatitis B, Hepatitis C, mycoplasma, bacteria, and fungi.

制备说明

  • Primary culture, >500,000 cells in Rat Keratinocyte Basal Medium that contains 10% FBS and 10% DMSO
  • These epithelial cells proliferate well when thawed and plated from cryopreservation, but they do not plate and proliferate after trypsinization

传代培养常规

Please refer to the RDF Culture Protocol.

基本信息

NACRESNA.81

产品性质

生物来源rat skin (Sprague Dawley)
质量水平100
包装pkg of 500,000 cells
生长模式Adherent
形态学Epidermal
technique(s)cell culture | mammalian: suitable
相关疾病allergies; cancer
运输dry ice
储存温度−196℃

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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