Oxatomide

产品名称：

60607-34-3
Oxatomide
1-[3-[4-(Diphenylmethyl)-1-piperazinyl]propyl]-1,3-dihydro-2H-benzimidazol-2-one

产品介绍：

产品说明

一般描述

Oxatomide, a histamine H1-receptor antagonist, is bound at high levels to plasma proteins in human blood.

生化/生理作用

Oxatomide, found in several antihistamines, can suppress mast cell degranulation. It can be used as an alternative to individuals with allergic rhinitis who do not or poorly respond to more established antihistamines. Oxatomide exhibits both antihistamine and anti-inflammatory properties. It exhibits therapeutic effects against asthma and vulvar lichen sclerosus.
Oxatomide is an anti-allergy compound. It suppresses platelet activating factor (PAF)-induced bronchoconstriction and inhibits leukotriene production.

特点和优势

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

基本信息

经验(实验)分子式	C₂₇H₃₀N₄O
分子量	426.55
EC 号	262-320-9
MDL编号	MFCD00211147
PubChem化学物质编号	24278615
NACRES	NA.77

产品性质

质量水平	100
测定	≥99%
颜色	white
溶解性	DMSO: soluble ethanol: soluble
创始人	Johnson & Johnson
SMILES string	O=C1Nc2ccccc2N1CCCN3CCN(CC3)C(c4ccccc4)c5ccccc5
InChI	1S/C27H30N4O/c32-27-28-24-14-7-8-15-25(24)31(27)17-9-16-29-18-20-30(21-19-29)26(22-10-3-1-4-11-22)23-12-5-2-6-13-23/h1-8,10-15,26H,9,16-21H2,(H,28,32)
InChI key	BAINIUMDFURPJM-UHFFFAOYSA-N
Gene Information	human ... DRD3(1814)

安全信息

象形图
警示用语：	Warning
危险声明	H302
危险分类	Acute Tox. 4 Oral
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves